General election
incumbent U.S. senator (1997–present)
- Graham Platner Democrat
Sullivan harbor master
Democratic primary
Sullivan harbor master
former deputy secretary of the Maryland Department of the Environment and nominee for U.S. Senate in 2024
Republican primary
incumbent U.S. senator (1997–present)
Party convention
- Ashley Webb Democrat
author, musician, and transgender activist
- Elizabeth Cote Democrat
health policy executive
- Elizabeth Dickerson Democrat
former state representative from the 93rd district (2012–2015) and former Rockland city councilor (2008–2012)
- Joseph Leveille Democrat
Marine Corps veteran
- Kristina Libby Democrat
writer, actor, and organizer
- Nirav Shah Democrat
former principal deputy director of the Centers for Disease Control and Prevention (2023–2025), former director of the Maine CDC (2019–2023), and candidate for governor in 2026
- Saundra Pelletier Democrat
healthcare executive
- Shenna Bellows Democrat
Maine secretary of state (2021–present), nominee for U.S. Senate in 2014, and candidate for governor in 2026
- Troy Jackson Democrat
former president of the Maine Senate (2018–2024), candidate for ME-02 in 2014, and candidate for governor in 2026
